Nature Search

Distinct glacial-interglacial amplitudes of Asian monsoon water isotopes during the last deglaciation

A weak glacial-interglacial isotopic signal in eastern China reflects compensatory processes in atmospheric moisture routing and local recycling, primarily orchestrated by ice-sheet forcing, according to speleothem records, climate simulations, and water-tagging experiments.

Xiaoqing Wang
Weiyi Sun
Yongjin Wang
ResearchOpen Access19 Feb 2026
Communications Earth & Environment

P: 1-10
ZDHHC11-mediated palmitoylation alleviates chondrocyte senescence and serves as a therapeutic target for osteoarthritis

Wang, He, Gong and colleagues identify an age-related decline in the palmitoyltransferase ZDHHC11 in chondrocytes that leads to senescence and the pathogenesis of osteoarthritis, highlighting the potential of targeted ZDHHC11 delivery as a therapeutic strategy for osteoarthritis.

Kefan Wang
Wei He
Shuying Shen
ResearchOpen Access30 Sept 2025
Nature Aging

Volume: 5, P: 2228-2246
Iminodiacetic acid modification enables nanopore identification of major divalent metal ions in natural water samples

A portable and affordable sensor based on iminodiacetic acid-modified nanopores can effectively detect a wide array of divalent metal ions, even within complex natural water environments.

Wen Sun
Tian Li
Shuo Huang
Research06 Jan 2026
Nature Water

Volume: 4, P: 58-67
Combined targeting of glioblastoma stem cells of different cellular states disrupts malignant progression

The molecular mechanisms underlying the function of different cellular states in glioblastoma stem cells (GSCs) remain poorly understood. Here, the authors perform integrated single cell and bulk analysis of GSCs and identify potential therapeutic targets.

Chenfei Lu
Tao Kang
Xiuxing Wang
ResearchOpen Access26 Mar 2025
Nature Communications

Volume: 16, P: 1-21
Unambiguous discrimination of all 20 proteinogenic amino acids and their modifications by nanopore

A Ni²⁺-modified MspA nanopore construct can unambiguously discriminate the 20 proteogenic amino acids as well as several post-translational modifications.

Kefan Wang
Shanyu Zhang
Shuo Huang
Research25 Sept 2023
Nature Methods

Volume: 21, P: 92-101
Nanopore discrimination of rare earth elements

Here the authors show that Mycobacterium smegmatis porin A modified with nitrilotriacetic acid achieves direct and simultaneous discrimination of rare earth elements, suggesting the potential use of nanopore sensing in geological exploration.

Wen Sun
Yunqi Xiao
Shuo Huang
Research10 Feb 2025
Nature Nanotechnology

Volume: 20, P: 523-531
Enhancing ferroelectric stability: wide-range of adaptive control in epitaxial HfO₂/ZrO₂ superlattices

By artificial superlattice design, the authors achieve stable polarization over wide frequency, temperature, and thickness ranges in epitaxial HfO₂/ZrO₂ superlattices, along with reduced coercive fields. This work offers a route to overcome polar phase metastability in HfO₂-based films.

Jingxuan Li
Shiqing Deng
Zuhuang Chen
ResearchOpen Access11 Jul 2025
Nature Communications

Volume: 16, P: 1-9
Ligand engineering towards electrocatalytic urea synthesis on a molecular catalyst

Electrocatalytic C-N coupling of carbon dioxide and nitrate offers a sustainable alternative to traditional urea production. Here the authors report amino substitution in copper phthalocyanine for enhanced urea electrosynthesis.

Han Li
Leitao Xu
Shuangyin Wang
ResearchOpen Access14 Oct 2024
Nature Communications

Volume: 15, P: 1-10
Linker-free PROTACs efficiently induce the degradation of oncoproteins

Linkers are traditionally seen as important for PROTAC activity. Here, the authors demonstrate that linker-free PROTACs can outperform traditional designs, marking a paradigm shift in PROTAC development for targeted protein degradation.

Jianchao Zhang
Congli Chen
Hai Rao
ResearchOpen Access23 May 2025
Nature Communications

Volume: 16, P: 1-15
An umbrella review of socioeconomic status and cancer

Socioeconomic status has been previously linked to cancer outcomes. Here, the authors use an umbrella review to identify differences in access to immunotherapy and cancer screening.

Shen Li
Yuxin He
Xuelei Ma
ResearchOpen Access18 Nov 2024
Nature Communications

Volume: 15, P: 1-13
Identification of nucleoside monophosphates and their epigenetic modifications using an engineered nanopore

A phenylboronic acid-modified hetero-octameric Mycobacterium smegmatis porin A nanopore can directly distinguish 11 types of nucleoside monophosphates with a 0.996 accuracy.

Yuqin Wang
Shanyu Zhang
Shuo Huang
Research18 Jul 2022
Nature Nanotechnology

Volume: 17, P: 976-983
Functional nano-architected mechanical metamaterials and devices

Kefan Guo
Yinong Li
Yang Lu
ReviewsOpen Access06 Jan 2026
npj Metamaterials

Volume: 2, P: 1-20
Tunable quantum gaps to decouple carrier and phonon transport leading to high-performance thermoelectrics

Defects are believed to always scatter carriers. Here, the authors find that the quantum gaps in GeTe-based materials do not scatter carriers, which decouple the carriers and phonons transport leading to high thermoelectric performance.

Yong Yu
Xiao Xu
Jiaqing He
ResearchOpen Access24 Sept 2022
Nature Communications

Volume: 13, P: 1-9
Dynamic transcriptomic and metabolomic adaptation mechanisms of Trifolium ambiguum under different durations of cold stress

Kefan Cao
Sijing Wang
Fan Huang
ResearchOpen Access31 Oct 2025
Scientific Reports

Volume: 15, P: 1-25
Microglial RUNX1/RBM47 ablation inhibits neuronal ferroptosis via regulating the cGAS-STING-MEF2C pathway in mice with postoperative cognitive dysfunction

Postoperative cognitive dysfunction (POCD) is linked to the activation of the cGAS-STING pathway. Here, the authors demonstrate that RUNX1-mediated upregulation of RBM47 enhances cGAS-STING signaling and neuronal ferroptosis, suggesting a potential therapeutic approach for POCD.

Shanshan Wang
Zankai Wu
Wei Wang
ResearchOpen Access17 Dec 2025
Communications Biology

Volume: 8, P: 1-18
High-efficiency, flexible and large-area red/green/blue all-inorganic metal halide perovskite quantum wires-based light-emitting diodes

Cao et al. reports highly efficient, flexible, and larger-area Red/Green/Blue perovskite light-emitting diodes based on all-inorganic metal halide perovskite quantum wires arrays fabricated by porous alumina membranes assisted solution method.

Yang Bryan Cao
Daquan Zhang
Zhiyong Fan
ResearchOpen Access01 Aug 2023
Nature Communications

Volume: 14, P: 1-9
Improved efficiency of the biological pump as a trigger for the Late Ordovician glaciation

Enhanced algal productivity during the Late Ordovician may have led to carbon drawdown and the inception of the Hirnantian glaciation, according to sediment geochemistry and carbon cycle modelling.

Jiaheng Shen
Ann Pearson
Yanan Shen
Research11 Jun 2018
Nature Geoscience

Volume: 11, P: 510-514
Adaptive feature interaction enhancement network for text classification

Rui Su
Shangbing Gao
Junqiang Zhang
ResearchOpen Access03 Apr 2025
Scientific Reports

Volume: 15, P: 1-14
Mid-Cretaceous carbon cycle perturbations and Oceanic Anoxic Events recorded in southern Tibet

Xiaolin Zhang
Kefan Chen
Jingeng Sha
ResearchOpen Access21 Dec 2016
Scientific Reports

Volume: 6, P: 1-6
IFI35 regulates non-canonical NF-κB signaling to maintain glioblastoma stem cells and recruit tumor-associated macrophages

Daqi Li
Xiefeng Wang
Xiuxing Wang
Research09 Apr 2024
Cell Death & Differentiation

Volume: 31, P: 738-752
RBM15-mediated N6-methyladenosine modification affects COVID-19 severity by regulating the expression of multitarget genes

Yuting Meng
Qiong Zhang
Hongyan Diao
ResearchOpen Access23 Jul 2021
Cell Death & Disease

Volume: 12, P: 1-10
GSTM3 enhances radiosensitivity of nasopharyngeal carcinoma by promoting radiation-induced ferroptosis through USP14/FASN axis and GPX4

Yuting Chen
Yuanyuan Feng
Longmei Cai
ResearchOpen Access16 Jan 2024
British Journal of Cancer

Volume: 130, P: 755-768
Galectin-3 is involved in inflammation and fibrosis in arteriogenic erectile dysfunction via the TLR4/MyD88/NF-κB pathway

Guanbo Wang
Ruiyu Li
Qiang Fu
ResearchOpen Access20 Feb 2024
Cell Death Discovery

Volume: 10, P: 1-11
Different gap junction-propagated effects on cisplatin transfer result in opposite responses to cisplatin in normal cells versus tumor cells

Yuan Zhang
Liang Tao
Qin Wang
ResearchOpen Access28 Jul 2015
Scientific Reports

Volume: 5, P: 1-12

Search

Distinct glacial-interglacial amplitudes of Asian monsoon water isotopes during the last deglaciation

ZDHHC11-mediated palmitoylation alleviates chondrocyte senescence and serves as a therapeutic target for osteoarthritis

Iminodiacetic acid modification enables nanopore identification of major divalent metal ions in natural water samples

Combined targeting of glioblastoma stem cells of different cellular states disrupts malignant progression

Unambiguous discrimination of all 20 proteinogenic amino acids and their modifications by nanopore

Nanopore discrimination of rare earth elements

Enhancing ferroelectric stability: wide-range of adaptive control in epitaxial HfO₂/ZrO₂ superlattices

Ligand engineering towards electrocatalytic urea synthesis on a molecular catalyst

Linker-free PROTACs efficiently induce the degradation of oncoproteins

An umbrella review of socioeconomic status and cancer

Identification of nucleoside monophosphates and their epigenetic modifications using an engineered nanopore

Functional nano-architected mechanical metamaterials and devices

Tunable quantum gaps to decouple carrier and phonon transport leading to high-performance thermoelectrics

Dynamic transcriptomic and metabolomic adaptation mechanisms of Trifolium ambiguum under different durations of cold stress

Microglial RUNX1/RBM47 ablation inhibits neuronal ferroptosis via regulating the cGAS-STING-MEF2C pathway in mice with postoperative cognitive dysfunction

High-efficiency, flexible and large-area red/green/blue all-inorganic metal halide perovskite quantum wires-based light-emitting diodes

Improved efficiency of the biological pump as a trigger for the Late Ordovician glaciation

Adaptive feature interaction enhancement network for text classification

Mid-Cretaceous carbon cycle perturbations and Oceanic Anoxic Events recorded in southern Tibet

IFI35 regulates non-canonical NF-κB signaling to maintain glioblastoma stem cells and recruit tumor-associated macrophages

RBM15-mediated N6-methyladenosine modification affects COVID-19 severity by regulating the expression of multitarget genes

GSTM3 enhances radiosensitivity of nasopharyngeal carcinoma by promoting radiation-induced ferroptosis through USP14/FASN axis and GPX4

Galectin-3 is involved in inflammation and fibrosis in arteriogenic erectile dysfunction via the TLR4/MyD88/NF-κB pathway

Different gap junction-propagated effects on cisplatin transfer result in opposite responses to cisplatin in normal cells versus tumor cells

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