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Showing 1–12 of 12 results
Advanced filters: Author: Kehan Zhou Clear advanced filters

  • Large language models are starting to be used in safety-critical tasks such as controlling robots. Zhou et al. present LabSafety Bench, a benchmark evaluating the ability of large language models to identify hazards and assess laboratory risks.

    • Yujun Zhou
    • Jingdong Yang
    • Xiangliang Zhang
    Research
    Nature Machine Intelligence
    Volume: 8, P: 20-31

  • Enantioselective introduction of two different carbon-based functional groups in a single step using readily accessible and inexpensive starting materials presents a significant challenge. Here the authors report an electrochemical copper-catalyzed protocol for the asymmetric cyanoesterification of vinylarenes using commercially available alkyl carbazates and trimethylsilyl cyanide (TMSCN) as the sources of ester and cyano groups, respectively.

    • Kehan Zhou
    • Niankai Fu
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-8

  • Generative AI holds promise for creating novel compounds. Here, authors introduce TamGen, a GPT-like model designed to generate molecules tailored to specific target proteins. TamGen identified 14 potent compounds against the Tuberculosis ClpP protease, showing its potential for drug discovery.

    • Kehan Wu
    • Yingce Xia
    • Tie-Yan Liu
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-12

  • To overcome various challenges in forensic pathology, the authors present SongCi, a visual-language AI trained on multi-modal autopsy cases of various cohorts. SongCi detects diverse post-mortem diseases and injuries and gives clear image-text explanations for forensic analysis, rivaling senior pathologists.

    • Chen Shen
    • Chunfeng Lian
    • Zhenyuan Wang
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-20

  • Plant sulfate transporters mediate absorption and distribution of sulfate. Here the authors present functional assays and a cryo-EM structure of the Arabidopsis SULTR4;1 transporter identifying key domains for dimerization, substrate binding and coupling of transport activity to a proton gradient.

    • Lie Wang
    • Kehan Chen
    • Ming Zhou
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-8

  • The large-scale fabrication of twisted van der Waals heterostructures remains challenging due to the formation of defects and contaminations during the transfer process. Here, the authors report a transfer method to fabricate graphene-based van der Waals superlattices at the wafer scale, showing controllable twist angles and robust quantum Hall effect.

    • Guowen Yuan
    • Weilin Liu
    • Libo Gao
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-10

  • The treatment of hypertrophic scar (HS) is hindered by the low bioavailability of drugs and the pathological microenvironment. Here the authors report a separating microneedle drug delivery system responsive to high reactive oxygen species levels and overexpression of matrix metalloproteinases to remodel the pathological microenvironment for HS treatment.

    • Zhuo-Ran Yang
    • Huinan Suo
    • Jintao Zhu
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-17

  • Question Answering (QA) models have emerged as crucial tools for acquiring knowledge and evaluating domain-specific abilities, however, the domain of chemical QA remains underexplored. Here, the authors report ScholarChemQA as a large-scale QA dataset and introduce a ChemMatch model for effectively answering chemical questions and acquiring chemical-related knowledge.

    • Xiuying Chen
    • Tairan Wang
    • Xiangliang Zhang
    ResearchOpen Access
    Communications Chemistry
    Volume: 8, P: 1-11

  • In an inter-laboratory study, the authors compare the accuracy and performance of three optical density calibration protocols (colloidal silica, serial dilution of silica microspheres, and colony-forming unit (CFU) assay). They demonstrate that serial dilution of silica microspheres is the best of these tested protocols, allowing precise and robust calibration that is easily assessed for quality control and can also evaluate the effective linear range of an instrument.

    • Jacob Beal
    • Natalie G. Farny
    • Jiajie Zhou
    ResearchOpen Access
    Communications Biology
    Volume: 3, P: 1-29