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Communications Biology (2)
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Showing 1–3 of 3 results

Advanced filters: Author: Kelly M. Crebs Clear advanced filters

PPM1D suppresses p53-dependent transactivation and cell death by inhibiting the Integrated Stress Response

The authors describe a functional crosstalk between the p53 network and the integrated stress response through the p53 repressor PPM1D. Inhibition of PPM1D potentiates p53-dependent transactivation and apoptosis via induction of the HRI-eIF2α-ATF4 pathway.

Zdenek Andrysik
Kelly D. Sullivan
Joaquin M. Espinosa
ResearchOpen Access01 Dec 2022
Nature Communications

Volume: 13, P: 1-16
Lifespan-extending interventions induce consistent patterns of fatty acid oxidation in mouse livers

Integrated systems analysis on mouse liver proteomic and transcriptomic data of multiple lifespan-extending interventions highlights the overarching biological processes involved in aging and longevity.

Kengo Watanabe
Tomasz Wilmanski
Noa Rappaport
ResearchOpen Access22 Jul 2023
Communications Biology

Volume: 6, P: 1-15
Author Correction: Lifespan-extending interventions induce consistent patterns of fatty acid oxidation in mouse livers

Kengo Watanabe
Tomasz Wilmanski
Noa Rappaport
Amendments and CorrectionsOpen Access27 Nov 2023
Communications Biology

Volume: 6, P: 1

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PPM1D suppresses p53-dependent transactivation and cell death by inhibiting the Integrated Stress Response

Lifespan-extending interventions induce consistent patterns of fatty acid oxidation in mouse livers

Author Correction: Lifespan-extending interventions induce consistent patterns of fatty acid oxidation in mouse livers

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