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Showing 1–5 of 5 results
Advanced filters: Author: Kelly Wetmore Clear advanced filters

  • A genome-wide transposon screen in Halothiobacillus neapolitanus identifies genes involved in CO2 concentrating mechanisms, of which dabA and dabB encode a heterodimeric complex that works as an energy-coupled inorganic carbon pump. Dab homologues exist in multiple archaea and bacteria, including pathogens such as Bacillus anthracis and Vibrio cholerae.

    • John J. Desmarais
    • Avi I. Flamholz
    • David F. Savage
    Research
    Nature Microbiology
    Volume: 4, P: 2204-2215

  • Fitness landscapes largely shape the dynamics of evolution, but it is unclear how they shift upon ecological diversification. By engineering genome-wide knockout libraries of a nascent bacterial community, Ascensao et al. show how ecological and epistatic patterns combine to shape adaptive landscapes.

    • Joao A. Ascensao
    • Kelly M. Wetmore
    • Oskar Hallatschek
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-19

  • Levulinic acid (LA) is a value-added chemical easily obtained from biomass. The pathway enabling LA degradation in Pseudomonas putida requires five enzymes and can be engineered into Escherichia coli, which could enable further biotechnological applications.

    • Jacqueline M. Rand
    • Tippapha Pisithkul
    • Brian F. Pfleger
    Research
    Nature Microbiology
    Volume: 2, P: 1624-1634