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Showing 1–2 of 2 results
Advanced filters: Author: Keren Shemesh Clear advanced filters

  • The extracellular Contractile Injection System (eCIS) is a toxin-delivery particle that mediates interactions between bacteria and their invertebrate hosts. Here, the authors catalogue eCIS loci from 1,249 prokaryotic genomes, showing enrichment in non-pathogenic environmental microbes, and identifying eCIS-associated toxins that inhibit the growth of bacteria and/or yeast.

    • Alexander Martin Geller
    • Inbal Pollin
    • Asaf Levy
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-15

  • Comprehensive mutation libraries are an invaluable resource for screens in yeast, but anecdotal cases link phenotypes to the neighbor of a mutated gene rather than the mutant itself. The authors show that the neighboring gene effect is widespread and present software that uses protein-protein interaction networks to predict it.

    • Taly Ben-Shitrit
    • Nir Yosef
    • Martin Kupiec
    Research
    Nature Methods
    Volume: 9, P: 373-378