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Advanced filters: Author: Kevin E. Loewke Clear advanced filters

Non-invasive imaging of human embryos before embryonic genome activation predicts development to the blastocyst stage

The grading systems used by in vitro fertilization clinics cannot determine reliably whether a given embryo will lead to a successful pregnancy. Wong et al. address one part of this problem by showing that development of an embryo to the blastocyst stage can be predicted with high confidence at day 2 post fertilization.

Connie C Wong
Kevin E Loewke
Renee A Reijo Pera
Research03 Oct 2010
Nature Biotechnology

Volume: 28, P: 1115-1121
Dynamic blastomere behaviour reflects human embryo ploidy by the four-cell stage

Abnormal human embryo development is implicated in the embryo arrest observed during in vitrofertilization. Chavez and colleagues perform time-lapse imaging on human embryos and find that chromosomally abnormal embryos exhibit diverse cell cycle parameters that may contribute to arrest.

Shawn L. Chavez
Kevin E. Loewke
Renee A. Reijo Pera
ResearchOpen Access04 Dec 2012
Nature Communications

Volume: 3, P: 1-12
Optimizing oocyte yield utilizing a machine learning model for dose and trigger decisions, a multi-center, prospective study

Chelsea Canon
Lily Leibner
David Hoffman
ResearchOpen Access20 Aug 2024
Scientific Reports

Volume: 14, P: 1-8

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