Nature Search

Reply to ‘Mosaic loss of chromosome Y in leukocytes matters’

Weiyin Zhou
Mitchell J. Machiela
Stephen J. Chanock
Correspondence04 Dec 2018
Nature Genetics

Volume: 51, P: 7-9
Bacterial phylogeny structures soil resistomes across habitats

Functional metagenomic selections for resistance to 18 antibiotics in 18 different soils reveal that bacterial community composition is the primary determinant of soil antibiotic resistance gene content.

Kevin J. Forsberg
Sanket Patel
Gautam Dantas
Research21 May 2014
Nature

Volume: 509, P: 612-616
Prediction of the intestinal resistome by a three-dimensional structure-based method

Development of a structure-based method to predict potential ARDs present in human metagenomes indicates that resistance genes are rarely transferred within the human gut, and that individuals can be clustered into resistotypes.

Etienne Ruppé
Amine Ghozlane
S. Dusko Ehrlich
Research26 Nov 2018
Nature Microbiology

Volume: 4, P: 112-123
Proton irradiation-decelerated intergranular corrosion of Ni-Cr alloys in molten salt

Better understanding the synergy between radiation and corrosion is necessary to deploy advanced nuclear reactors. Here, the authors contradict the misconception that radiation always results in deleterious effects and show that proton irradiation slows the corrosion of Ni-Cr alloys in 650 °C molten salt.

Weiyue Zhou
Yang Yang
Michael P. Short
ResearchOpen Access09 Jul 2020
Nature Communications

Volume: 11, P: 1-7
Deciphering distinct genetic risk factors for FTLD-TDP pathological subtypes via whole-genome sequencing

Here the authors identify TNIP1 as a risk factor for a fatal neurodegenerative disorder and discover specific genetic loci associated with the three main subtypes of this disorder. The findings highlight distinct disease mechanisms, emphasizing the roles of immunity and the notch signaling pathway.

Cyril Pottier
Fahri Küçükali
Rosa Rademakers
ResearchOpen Access25 Apr 2025
Nature Communications

Volume: 16, P: 1-19
Lung adenocarcinoma promotion by air pollutants

Combination of epidemiology, preclinical models and ultradeep DNA profiling of clinical cohorts unpicks the inflammatory mechanism by which air pollution promotes lung cancer

William Hill
Emilia L. Lim
Charles Swanton
Research05 Apr 2023
Nature

Volume: 616, P: 159-167
Improved annotation of antibiotic resistance determinants reveals microbial resistomes cluster by ecology

Molly K Gibson
Kevin J Forsberg
Gautam Dantas
Research08 Jul 2014
The ISME Journal

Volume: 9, P: 207-216
Publisher Correction: Shared strategies for β-lactam catabolism in the soil microbiome

Terence S. Crofts
Bin Wang
Gautam Dantas
Amendments and Corrections27 Dec 2018
Nature Chemical Biology

Volume: 15, P: 206
Small protein modules dictate prophage fates during polylysogeny

Prophage lysogeny-to-lysis transitions are controlled by regulatory modules consisting of transcription factors and partner small proteins that are activated through DNA-damage-independent pathways, including by quorum sensing, and these modules determine inter-prophage competition outcomes.

Justin E. Silpe
Olivia P. Duddy
Bonnie L. Bassler
ResearchOpen Access26 Jul 2023
Nature

Volume: 620, P: 625-633
Mosaic loss of chromosome Y in blood is associated with male susceptibility for idiopathic pulmonary fibrosis

Bjurling et al. evaluate mosaic loss of chromosome Y (mLOY) as a risk factor for male idiopathic pulmonary fibrosis (IPF) in epidemiological, clinical, and single-cell RNA sequencing data. The results suggest that mLOY contributes to IPF severity by enhancing profibrotic signaling in lung tissues, highlighting the potential for targeted therapies.

Josefin Bjurling
Nicholas W. Chavkin
Lars A. Forsberg
ResearchOpen Access28 Jun 2025
Communications Medicine

Volume: 5, P: 1-10
Shared strategies for β-lactam catabolism in the soil microbiome

A β-lactamase, a novel type of amidase, and the phenylacetic acid catabolon comprise a catabolic pathway, revealed by genomic and transcriptomic analysis, that enables multiple soil bacteria to use β-lactam antibiotics as a carbon source.

Terence S. Crofts
Bin Wang
Gautam Dantas
Research30 Apr 2018
Nature Chemical Biology

Volume: 14, P: 556-564
Comparison of sequencing-based methods to profile DNA methylation and identification of monoallelic epigenetic modifications

Methods for profiling DNA methylation differ in the physical principles used to detect modified cytosines. Harris et al. compare the performances of four sequencing-based technologies for genome-wide analysis of DNA methylation and combine two methods to enable detection of allelic differences in epigenetic marks.

R Alan Harris
Ting Wang
Joseph F Costello
Research19 Sept 2010
Nature Biotechnology

Volume: 28, P: 1097-1105

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