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  • The small heat shock protein αB-crystallin is a major immune target in multiple sclerosis patients. This paper provides evidence that αB-crystallin is an anti-inflammatory and neuroprotective factor and that the immune response against it promotes disease by limiting its availability.

    • Shalina S. Ousman
    • Beren H. Tomooka
    • Lawrence Steinman
    Research
    Nature
    Volume: 448, P: 474-479