Accumulating evidence has challenged the dogma of monocytes as short-lived macrophage precursors. Monocyte populations are heterogeneous and have subset-specific functions. This Review provides an updated view of the role of monocytes in cardiovascular disease and their relationship with macrophages, highlighting current theories on monocyte ontogeny, and discussing the effects of dyslipidaemia on monocyte production, phenotype, and function.
- Mohammed Shamim Rahman
- Andrew J. Murphy
- Kevin J. Woollard
