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Advanced filters: Author: Kiarash Shamardani Clear advanced filters

Glioblastoma remodelling of human neural circuits decreases survival

High-grade gliomas functionally remodel neural circuits in the human brain, promoting tumour progression and impairing cognition.

Saritha Krishna
Abrar Choudhury
Shawn L. Hervey-Jumper
ResearchOpen Access03 May 2023
Nature

Volume: 617, P: 599-607
GABAergic neuron-to-glioma synapses in diffuse midline gliomas

Functional, tumour-promoting GABAergic neuron-to-glioma synapses in diffuse midline gliomas are identified.

Tara Barron
Belgin Yalçın
Michelle Monje
ResearchOpen Access19 Feb 2025
Nature

Volume: 639, P: 1060-1068
Myelin plasticity in the ventral tegmental area is required for opioid reward

Oligodendrogenesis is shown to be involved in reward learning, with dopaminergic neuronal activity-regulated myelin plasticity being an important reward circuit modification.

Belgin Yalçın
Matthew B. Pomrenze
Michelle Monje
ResearchOpen Access05 Jun 2024
Nature

Volume: 630, P: 677-685
Glioma synapses recruit mechanisms of adaptive plasticity

In glioma, malignant synapses hijack mechanisms of synaptic plasticity to increase glutamate-dependent currents in tumour cells and the formation of neuron–glioma synapses, thereby promoting tumour proliferation and progression.

Kathryn R. Taylor
Tara Barron
Michelle Monje
ResearchOpen Access01 Nov 2023
Nature

Volume: 623, P: 366-374
The logic of recurrent circuits in the primary visual cortex

Using two-photon (2P) optogenetics and computational modeling, the authors find that neither space-based nor feature-based rules are sufficient to describe cell–cell interactions within the primary visual cortex (V1). Instead, models must include interactions between these cardinal axes.

Ian Antón Oldenburg
William D. Hendricks
Hillel Adesnik
ResearchOpen Access03 Jan 2024
Nature Neuroscience

Volume: 27, P: 137-147