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Showing 1–2 of 2 results
Advanced filters: Author: Kiersten M. Ruff Clear advanced filters

  • In this work, the authors report that protein-RNA condensates with shared proteins and distinct RNAs can form and persist in vitro and in cells as distinct entities if the nonshared RNA molecules are dynamically arrested, but the shared protein components are dynamically exchangeable.

    • Andrew Z. Lin
    • Kiersten M. Ruff
    • Rohit V. Pappu
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-17

  • Transcriptional condensates concentrate gene regulatory proteins to control gene activation. Meyer et al. demonstrate that charge-mediated co-condensation of YAP and the oppositely charged transcriptional scaffold Med1 drives transcriptional activation.

    • Kirstin Meyer
    • Klaus Yserentant
    • Orion D. Weiner
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-16