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Showing 51–100 of 108 results

Advanced filters: Author: Kim D. Ferrari Clear advanced filters

Shear-stress sensing by PIEZO1 regulates tendon stiffness in rodents and influences jumping performance in humans

The mechanosensitive ion channel PIEZO1 senses shear stress induced by collagen-fibre sliding in tendons, regulates their stiffness and influences jumping performance.

Fabian S. Passini
Patrick K. Jaeger
Jess G. Snedeker
Research24 May 2021
Nature Biomedical Engineering

Volume: 5, P: 1457-1471
Arousal-induced cortical activity triggers lactate release from astrocytes

Zuend and colleagues show that an arousal-induced increase in cortical activity is accompanied by a surge in lactate in the extracellular space and a substantial lactate dip in astrocytes, followed by mobilization of lactate from glycogen stores and neuronal lactate increase.

Marc Zuend
Aiman S. Saab
Bruno Weber
Research17 Feb 2020
Nature Metabolism

Volume: 2, P: 179-191
Vaccine protection against acquisition of neutralization-resistant SIV challenges in rhesus monkeys

Protective efficacy of novel vaccine candidates in rhesus monkeys opens new paths for the development of an HIV-1 vaccine.

Dan H. Barouch
Jinyan Liu
Nelson L. Michael
Research04 Jan 2012
Nature

Volume: 482, P: 89-93
Shear band-driven precipitate dispersion for ultrastrong ductile medium-entropy alloys

Precipitation hardening, used as an effective strengthening strategy in various alloy systems, has been usually achieved by coherent precipitates. Here, the authors develop ultrastrong ductile alloys employing structurally dissimilar semicoherent precipitates by shear band-driven precipitation.

Tae Jin Jang
Won Seok Choi
Seok Su Sohn
ResearchOpen Access04 Aug 2021
Nature Communications

Volume: 12, P: 1-9
Association of interleukin-6 promoter variant with bone mineral density in pre-menopausal women

Hye Won Chung
Jeong-Sun Seo
Hyoung Doo Shin
Research18 Apr 2003
Journal of Human Genetics

Volume: 48, P: 243-248
Ultrasensitive detection of nucleic acids using deformed graphene channel field effect biosensors

Field effect transistors based on graphene hold promise for sensing applications. Here, the authors report a millimeter-sized transistor based on deformed graphene as a biosensor that can detect nucleic acid molecules having detection limit of ~18 molecules of DNA in physiological buffer solution and ~600 molecules in human serum.

Michael Taeyoung Hwang
Mohammad Heiranian
Rashid Bashir
ResearchOpen Access24 Mar 2020
Nature Communications

Volume: 11, P: 1-11
Chronic stress in mice remodels lymph vasculature to promote tumour cell dissemination

Adverse life events have been associated with reduced survival in cancer patients. Here, the authors explore the mechanism responsible and show that chronic stress in mice activates a signalling cascade in macrophages and tumour cells, which results in restructuring of the tumour lymphatic system, promoting metastasis.

Caroline P. Le
Cameron J. Nowell
Erica K. Sloan
ResearchOpen Access01 Mar 2016
Nature Communications

Volume: 7, P: 1-14
Confocal reference free traction force microscopy

Traction force microscopy is an effective method of measuring forces between cells and their environment, but requires removing the cells to obtain a reference image. Here the authors use nanodrip printing of quantum dots into compliant substrates to provide a regular array of fiducial spots, removing the need for a reference image.

Martin Bergert
Tobias Lendenmann
Aldo Ferrari
ResearchOpen Access29 Sept 2016
Nature Communications

Volume: 7, P: 1-10
DNA-conformation is an important determinant of sequence-specific DNA binding by tumor suppressor p53

Ella Kim
Nils Albrechtsen
Wolfgang Deppert
Research14 Aug 1997
Oncogene

Volume: 15, P: 857-859
Ascorbic acid prevents loss of Dlk1-Dio3 imprinting and facilitates generation of all–iPS cell mice from terminally differentiated B cells

Konrad Hochedlinger and colleagues show that ascorbic acid enhances cellular reprogramming by preventing hypermethylation of the imprinted Dlk1-Dio3 locus. They use this approach to generate adult mice derived entirely from induced pluripotent stem cells obtained through reprogramming of terminally differentiated B cells.

Matthias Stadtfeld
Effie Apostolou
Konrad Hochedlinger
Research04 Mar 2012
Nature Genetics

Volume: 44, P: 398-405
Genetic identification of cell types underlying brain complex traits yields insights into the etiology of Parkinson’s disease

Integration of GWAS and single-cell transcriptomic data from the entire nervous system systematically identifies cell types underlying brain complex traits and provides insights into the etiology of Parkinson’s disease.

Julien Bryois
Nathan G. Skene
Patrick F. Sullivan
Research27 Apr 2020
Nature Genetics

Volume: 52, P: 482-493
Dynamic molecular changes during the first week of human life follow a robust developmental trajectory

The first week of life impacts health for all of life, but the mechanisms are little-understood. Here the authors extract multi-omic data from small volumes of blood to study the dynamic molecular changes during the first week of life, revealing a robust developmental trajectory common to different populations.

Amy H. Lee
Casey P. Shannon
Tobias R. Kollmann
ResearchOpen Access12 Mar 2019
Nature Communications

Volume: 10, P: 1-14
ALFQ adjuvanted HIV-1 envelope protein vaccination elicits durable functional antibody and cellular responses in nonhuman primates

Shikha Shrivastava
Joshua M. Carmen
Mangala Rao
ResearchOpen Access19 Dec 2025
npj Vaccines

Volume: 11, P: 1-21
Microglia, major player in the brain inflammation: their roles in the pathogenesis of Parkinson's disease

Yoon Seong Kim
Tong H Joh
ReviewsOpen Access01 Aug 2006
Experimental & Molecular Medicine

Volume: 38, P: 333-347
Uncovering the heterogeneity and temporal complexity of neurodegenerative diseases with Subtype and Stage Inference

Progressive diseases tend to be heterogeneous in their underlying aetiology mechanism, disease manifestation, and disease time course. Here, Young and colleagues devise a computational method to account for both phenotypic heterogeneity and temporal heterogeneity, and demonstrate it using two neurodegenerative disease cohorts.

Alexandra L Young
Razvan V Marinescu
Ansgar J Furst
ResearchOpen Access15 Oct 2018
Nature Communications

Volume: 9, P: 1-16
Genetic correlation between amyotrophic lateral sclerosis and schizophrenia

Relatives of patients with amyotrophic lateral sclerosis have an unexpectedly high incidence of schizophrenia. Here, the authors show a genetic link between the two conditions, suggesting shared neurobiological mechanisms.

Russell L. McLaughlin
Dick Schijven
Michael C. O’Donovan
ResearchOpen Access21 Mar 2017
Nature Communications

Volume: 8, P: 1-12
On the issue of transparency and reproducibility in nanomedicine

Following our call to join in the discussion over the suitability of implementing a reporting checklist for bio–nano papers, the community responds.

Hon S. Leong
Kimberly S. Butler
Chiara Pastore
Correspondence03 Jul 2019
Nature Nanotechnology

Volume: 14, P: 629-635
Heart rate: a forgotten link in coronary artery disease?

Elevated resting heart rate is an independent, modifiable risk factor for cardiovascular events and mortality in patients with coronary artery disease (CAD). Several mechanisms by which elevated heart rate adversely affects the cardiovascular system are now known. Rates of adequate heart rate control appear to be low in current clinical practice, potentially representing a missed therapeutic opportunity. Drs. Fox and Ferrari discuss the mechanisms that might underlie the involvement of heart rate in CAD and other conditions and review the results of randomized trials that have emphasized its clinical importance.

Kim M. Fox
Roberto Ferrari
Reviews26 Apr 2011
Nature Reviews Cardiology

Volume: 8, P: 369-379
Author Correction: A detailed map of Higgs boson interactions by the ATLAS experiment ten years after the discovery

G. Aad
B. Abbott
L. Zwalinski
Amendments and CorrectionsOpen Access18 Oct 2023
Nature

Volume: 623, P: E5
Feasibility of oral doxycycline as first-line therapy for conjunctival mucosa-associated lymphoid tissue lymphoma

Se Hyun Choi
Min Kyu Yang
Hyuk Jin Choi
Research23 Jun 2023
Eye

Volume: 38, P: 82-88
Enhanced CAR T cell expansion and prolonged persistence in pediatric patients with ALL treated with a low-affinity CD19 CAR

New low-affinity anti-CD19 CAR T cells exhibit peripheral expansion and persistence without inducing severe cytokine-response syndrome in pediatric patients with relapsed or refractory B cell acute lymphoblastic leukemia.

Sara Ghorashian
Anne Marijn Kramer
Persis J. Amrolia
Research02 Sept 2019
Nature Medicine

Volume: 25, P: 1408-1414
Author Correction: A joint international consensus statement for measuring quality of survival for patients with childhood cancer

Rebecca J. van Kalsbeek
Melissa M. Hudson
Lisa Zwiers
Amendments and Corrections22 May 2024
Nature Medicine

Volume: 30, P: 2091
Publisher Correction: On the issue of transparency and reproducibility in nanomedicine

Hon S. Leong
Kimberly S. Butler
Chiara Pastore
Amendments and Corrections29 Jul 2019
Nature Nanotechnology

Volume: 14, P: 902
Publisher Correction: On the issue of transparency and reproducibility in nanomedicine

Hon S. Leong
Kimberly S. Butler
Chiara Pastore
Amendments and Corrections09 Jul 2019
Nature Nanotechnology

Volume: 14, P: 811
Folate intake and the risk of colorectal cancer in a Korean population

J Kim
D H Kim
Y O Ahn
Research24 Jun 2009
European Journal of Clinical Nutrition

Volume: 63, P: 1057-1064
Mutations in kelch-like 3 and cullin 3 cause hypertension and electrolyte abnormalities

Exome sequencing identifies mutations in kelch-like 3 and cullin 3 as causes of a syndrome featuring high blood pressure and electrolyte abnormalities.

Lynn M. Boyden
Murim Choi
Richard P. Lifton
Research22 Jan 2012
Nature

Volume: 482, P: 98-102
A complete pupillometry toolbox for real-time monitoring of locus coeruleus activity in rodents

Pupil diameter is measured in rodents using low-cost cameras and a Raspberry Pi computer to obtain a rapid, noninvasive real-time readout of locus coeruleus activity.

Mattia Privitera
Kim David Ferrari
Johannes Bohacek
Protocols06 Jul 2020
Nature Protocols

Volume: 15, P: 2301-2320
Comparative analysis of metazoan chromatin organization

A large collection of new modENCODE and ENCODE genome-wide chromatin data sets from cell lines and developmental stages in worm, fly and human are analysed; this reveals many conserved features of chromatin organization among the three organisms, as well as notable differences in the composition and locations of repressive chromatin.

Joshua W. K. Ho
Youngsook L. Jung
Peter J. Park
ResearchOpen Access27 Aug 2014
Nature

Volume: 512, P: 449-452
Mechanical behaviour of granular materials undergoing grain dissolution

Taeheon Kim
Alessio Ferrari
Lyesse Laloui
ResearchOpen Access19 Sept 2024
Scientific Reports

Volume: 14, P: 1-15
Aim, design and methods of the ‘reasons for not intensifying antihypertensive treatment’ (RIAT): an international registry in essential hypertension

P Ferrari
S-K Kim
R Esper
Research27 Oct 2005
Journal of Human Hypertension

Volume: 20, P: 31-36
A joint international consensus statement for measuring quality of survival for patients with childhood cancer

The International Childhood Cancer Outcome Project group, involving survivors and other relevant stakeholders, develop a set of core outcomes to measure the quality of care for 17 types of childhood cancers.

Rebecca J. van Kalsbeek
Melissa M. Hudson
Lisa Zwiers
Reviews15 Jun 2023
Nature Medicine

Volume: 29, P: 1340-1348
Transmission of Metarhizium anisopliae and Beauveria bassiana to adults of Kuschelorhynchus macadamiae (Coleoptera: Curculionidae) from infected adults and conidiated cadavers

Kim Khuy Khun
Gavin J. Ash
Bree A. L. Wilson
ResearchOpen Access26 Jan 2021
Scientific Reports

Volume: 11, P: 1-12
Economic costs at age five for very preterm children with congenital anomalies: evidence from a European cohort

Sung Wook Kim
Veronica Siljehav
A. V. Seppänen
ResearchOpen Access07 Jan 2026
Pediatric Research

P: 1-8
Implication of the glutamate–cystine antiporter xCT in schizophrenia cases linked to impaired GSH synthesis

M. Fournier
A. Monin
K. Do
ResearchOpen Access18 Sept 2017
npj Schizophrenia

Volume: 3, P: 1-7
Author Correction: A joint international consensus statement for measuring quality of survival for patients with childhood cancer

Rebecca J. van Kalsbeek
Melissa M. Hudson
Lisa Zwiers
Amendments and Corrections13 Dec 2023
Nature Medicine

Volume: 30, P: 605
Angiotensin II Type 1 Receptor Blocker Prevents Atrial Structural Remodeling in Rats with Hypertension Induced by Chronic Nitric Oxide Inhibition

Hidetoshi Okazaki
Tetsuo Minamino
Masafumi Kitakaze
Research01 Apr 2006
Hypertension Research

Volume: 29, P: 277-284
Author Correction: A joint international consensus statement for measuring quality of survival for patients with childhood cancer

Rebecca J. van Kalsbeek
Melissa M. Hudson
Lisa Zwiers
Amendments and Corrections14 Nov 2023
Nature Medicine

Volume: 30, P: 603
Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis

Ammar Al-Chalabi, Jan Veldink and colleagues perform a genome-wide association study for amyotrophic lateral sclerosis (ALS) in 15,156 cases and 26,242 controls. They identify three new genome-wide-significant variants and establish ALS as a complex trait with a polygenic architecture, but with a distinct and important role for low-frequency variants.

Wouter van Rheenen
Aleksey Shatunov
Jan H Veldink
Research25 Jul 2016
Nature Genetics

Volume: 48, P: 1043-1048
Layered material platform for surface plasmon resonance biosensing

F. Wu
P. A. Thomas
A. N. Grigorenko
ResearchOpen Access30 Dec 2019
Scientific Reports

Volume: 9, P: 1-10
Fabrication and operation of GRIN probes for in vivo fluorescence cellular imaging of internal organs in small animals

Jun Ki Kim
Woei Ming Lee
Seok Hyun Yun
Protocols05 Jul 2012
Nature Protocols

Volume: 7, P: 1456-1469
Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis

Stephen Sawcer
Garrett Hellenthal
Alastair Compston
Research10 Aug 2011
Nature

Volume: 476, P: 214-219
The gephyrin scaffold modulates cortical layer 2/3 pyramidal neuron responsiveness to single whisker stimulation

Yuan-Chen Tsai
Mohammad Hleihil
Jillian L. Stobart
ResearchOpen Access20 Feb 2024
Scientific Reports

Volume: 14, P: 1-15
Stronger resting-state neural oscillations associated with wiser advising from the 2nd- but not the 3rd-person perspective

Chengli Huang
Haotian Zhang
Chao S. Hu
ResearchOpen Access29 Jul 2020
Scientific Reports

Volume: 10, P: 1-11
Author Correction: Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

Brian W. Kunkle
Benjamin Grenier-Boley
Margaret A. Pericak-Vance
Amendments and Corrections15 Aug 2019
Nature Genetics

Volume: 51, P: 1423-1424
Topology predicts long-term functional outcome in early psychosis

Margot Fournier
Martina Scolamiero
Kathryn Hess
ResearchOpen Access06 Jul 2020
Molecular Psychiatry

Volume: 26, P: 5335-5346
At-admission prediction of mortality and pulmonary embolism in an international cohort of hospitalised patients with COVID-19 using statistical and machine learning methods

Munib Mesinovic
Xin Ci Wong
David Zucman
ResearchOpen Access16 Jul 2024
Scientific Reports

Volume: 14, P: 1-43
Neuronal alpha-Synuclein Disease integrated staging system performance in PPMI, PASADENA, and SPARK baseline cohorts

Tien Dam
Gennaro Pagano
Dilinuer Wubuli
ResearchOpen Access27 Sept 2024
npj Parkinson's Disease

Volume: 10, P: 1-12
Body shape phenotypes of multiple anthropometric traits and cancer risk: a multi-national cohort study

Anja M. Sedlmeier
Vivian Viallon
Heinz Freisling
ResearchOpen Access02 Dec 2022
British Journal of Cancer

Volume: 128, P: 594-605
Isolation of mitochondria-derived mitovesicles and subpopulations of microvesicles and exosomes from brain tissues

This protocol describes the isolation from brain tissue of extracellular vesicle subpopulations, including microvesicles, exosomes and mitochondria-derived mitovesicles, using a high-resolution (iodixanol) density step gradient. Extracellular vesicle characterization and analysis are also presented.

Pasquale D’Acunzo
Yohan Kim
Efrat Levy
Protocols12 Aug 2022
Nature Protocols

Volume: 17, P: 2517-2549
A randomized phase 3 study of ixazomib–dexamethasone versus physician’s choice in relapsed or refractory AL amyloidosis

Angela Dispenzieri
Efstathios Kastritis
Giampaolo Merlini
ResearchOpen Access24 Jun 2021
Leukemia

Volume: 36, P: 225-235

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