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Showing 1–2 of 2 results
Advanced filters: Author: Kim Remans Clear advanced filters
  • Here, the authors isolate several nanobodies from a synthetic library that bind the receptor-binding domain (RBD) of SARS-CoV-2 spike protein (S) and neutralize S pseudotyped viruses. Cryo-EM structure of Spike with one nanobody and further biophysical analysis shows competition with ACE2 binding.

    • Tânia F. Custódio
    • Hrishikesh Das
    • Christian Löw
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-11
  • Proteins and peptides are amongst the most widely used research reagents but often their quality is inadequate and can result in poor data reproducibility. Here we propose a simple set of guidelines that, when correctly applied to protein reagents should provide more reliable experimental data.

    • Ario de Marco
    • Nick Berrow
    • Bertrand Raynal
    Comments & OpinionOpen Access
    Nature Communications
    Volume: 12, P: 1-4