This study describes burst-dependent protection from synaptic depression, which maintains responsiveness to behaviorally important stimuli in Aplysia. In this attention-like mechanism, PKC at sensory neuron synapses discriminates the precise pattern of firing, preventing these release sites from becoming silenced during repeated tactile stimuli when these stimuli are salient.
- Qin Wan
- Xue-Ying Jiang
- Thomas W Abrams