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Showing 1–2 of 2 results
Advanced filters: Author: Kirtana Ananth Clear advanced filters

  • An antibody screen of two distinct multiple sclerosis cohorts reveals an autoantibody signature that is detectable years before symptom onset and linked to a common microbial motif.

    • Colin R. Zamecnik
    • Gavin M. Sowa
    • Michael R. Wilson
    Research
    Nature Medicine
    Volume: 30, P: 1300-1308

  • The mechanisms that trigger neurodegeneration in demyelinating disease are unclear. Here, the authors find that impaired remyelination induces a DLK-mediated loss of retinal ganglion cells (RGCs), and that efficient remyelination or DLK inhibition block RGC death.

    • Greg J. Duncan
    • Sam D. Ingram
    • Ben Emery
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-19