Johnson and colleagues investigate spiking activity in developing inner hair cells (IHCs), showing that apical IHCs fire spontaneous action potentials in a burst-like pattern, whereas basal IHCs fire randomly. The burst-like firing of apical IHCs depends on acetylcholine. Extracellular ATP affects the resting potential of IHCs by activating SK2 channels.
- Stuart L Johnson
- Tobias Eckrich
- Walter Marcotti