In this study, the authors provide pre-clinical evaluation of immunogenicity of the “ChulaCov19” mRNA vaccine encoding the ectodomain of the SARS-CoV-2 S protein. The vaccine induced potent immune response when applied as homologous prime/boost immunization or as heterologous booster and protected mice from disease.
- Eakachai Prompetchara
- Chutitorn Ketloy
- Kiat Ruxrungtham