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Showing 1–3 of 3 results
Advanced filters: Author: Klement Stojanovski Clear advanced filters

  • In the nematode C. elegans, cohesin creates specifically at active enhancers chromatin 3D structures named fountains. Cohesin artificial cleavage disrupts fountains and changes neuronal gene expression, function and animal behavior.

    • Bolaji N. Lüthi
    • Jennifer I. Semple
    • Peter Meister
    ResearchOpen Access
    Nature Communications
    Volume: 17, P: 1-20

  • Imbalance in the growth rate of two organs can perturb their appropriate scaling. Here, Stojanovski et al., identify a mechanism involving the mechanotransducer YAP-1 which ensures proper proportions of the pharynx and the body length of C. elegans.

    • Klement Stojanovski
    • Ioana Gheorghe
    • Benjamin D. Towbin
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-13

  • Animals must reach the correct size during development, despite stochastic differences in their growth rate. Here, Stojanovski et al. show that a coupling of growth and development by an oscillatory timer buffers fluctuations in the growth of the nematode C. elegans to ensure its correct size.

    • Klement Stojanovski
    • Helge Großhans
    • Benjamin D. Towbin
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-14