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Showing 1–4 of 4 results

Advanced filters: Author: Kleopatra Avrampou Clear advanced filters

The stress response regulator HSF1 modulates natural killer cell anti-tumour immunity

Hockemeyer et al. demonstrate that HSF1 activation inhibits cytokine production and cytotoxic activity in NK cells to impair anti-tumour immune responses.

Kathryn Hockemeyer
Theodore Sakellaropoulos
Iannis Aifantis
Research02 Sept 2024
Nature Cell Biology

Volume: 26, P: 1734-1744
Valine tRNA levels and availability regulate complex I assembly in leukaemia

Restriction of dietary valine reduces growth of T cell acute lymphoblastic leukaemia through altered valine tRNA biogenesis and reduced translation of mRNAs that encode subunits of mitochondrial complex I.

Palaniraja Thandapani
Andreas Kloetgen
Iannis Aifantis
Research22 Dec 2021
Nature

Volume: 601, P: 428-433
Microglia and macrophages promote corralling, wound compaction and recovery after spinal cord injury via Plexin-B2

Zhou et al. unveil a novel role for activated microglia and macrophages during wound healing after CNS injury. Microglia promote corralling and form a protective barrier at the injury penumbra via the axon guidance receptor Plexin-B2.

Xiang Zhou
Shalaka Wahane
Hongyan Zou
Research28 Feb 2020
Nature Neuroscience

Volume: 23, P: 337-350
RGS9-2 Modulates Responses to Oxycodone in Pain-Free and Chronic Pain States

Sevasti Gaspari
Valeria Cogliani
Venetia Zachariou
Research11 Jan 2017
Neuropsychopharmacology

Volume: 42, P: 1548-1556