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Showing 1–3 of 3 results
Advanced filters: Author: Knud Jørgen Jensen Clear advanced filters
  • Peptide and oligonucleotide systems are known to self-assemble both in nature and artificial systems. Here, the authors combine both forms of self-assembly through the synthesis of peptideoligonucleotide conjugates and show formation of a three-helix structure that dimerises at higher concentrations.

    • Chenguang Lou
    • Manuel C. Martos-Maldonado
    • Knud J. Jensen
    ResearchOpen Access
    Nature Communications
    Volume: 7, P: 1-9
  • Conjugation of oligosaccharides to probes and surfaces is useful in the development of biochemical assays to assess carbohydrate–protein interactions. In this protocol, conjugation is enabled by using a bifunctional oligo(ethylene glycol) linker.

    • Christian T Hjuler
    • Nicolai N Maolanon
    • Knud J Jensen
    Protocols
    Nature Protocols
    Volume: 12, P: 2411-2422
  • Laursen et al. investigates the role of membrane anchoring for the organization and efficiency of P450-driven plant metabolism. They report an original experimental design to monitor interactions between anchoring segments of membrane-bound enzymes at the single molecule level, using the cytochrome P450 oxidoreductase (POR) transmembrane segment as a model, and propose that membrane anchoring has played a key role in the evolution of P450- based metabolic pathways in plants.

    • Tomas Laursen
    • Hiu Yue Monatrice Lam
    • Sune M. Christensen
    ResearchOpen Access
    Communications Biology
    Volume: 4, P: 1-9