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Advanced filters: Author: Kolin M. Clark Clear advanced filters

  • The non-nucleoside reverse transcriptase inhibitors (NNRTIs) drive HIV protease-mediated CARD8 inflammasome activation, which is attenuated by dipeptidyl peptidase 9 (DPP9). DPP9 inhibitors act synergistically with NNRTIs to clear HIV-infected cells.

    • Kolin M. Clark
    • Josh G. Kim
    • Liang Shan
    Research
    Nature Chemical Biology
    Volume: 19, P: 431-439