Understanding the structural dynamics of ribosomal components is key to understanding translation. The Z-DNA– and Z-RNA–binding domain from the human RNA editing enzyme ADAR1-L is now shown to bind to specific regions of ribosomal RNAs affecting translation, suggesting that these regions might at least transiently form Z-RNA structure not observed in crystal structures.
- Shu Feng
- Heng Li
- Peter Dröge
