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Showing 1–1 of 1 results
Advanced filters: Author: Kristiina Juvonen Clear advanced filters

  • The authors in this work identify an in vivo CNS active bifunctional degrader of GSK3. This was discovered via development of orthogonally reactive linker chemistry and a direct-to-biology screen that was able to provide hits of in vivo chemical probe quality.

    • Andreas Holmqvist
    • Nur Mehpare Kocaturk
    • William Farnaby
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-16