Adhesion GPCRs play a key role in cellular communication. Here, the authors use cryo-EM and single-molecule FRET to map the conformational changes between the extracellular and transmembrane domains of Latrophilin3/ADGRL3, offering new insights into receptor activation.
- Szymon P. Kordon
- Kristina Cechova
- Demet Araç
