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Showing 1–2 of 2 results
Advanced filters: Author: Kristine Germar Clear advanced filters

  • Ptacin et al. utilize a semi-synthetic microbial platform with an expanded genetic code to discover a PEGylated IL-2 compound that stimulates Tregs, with minimal effects on effector populations. Studies in mice and primates demonstrate Treg stimulation and support development of this compound for the potential treatment of autoimmune diseases.

    • Jerod L. Ptacin
    • Lina Ma
    • Marcos E. Milla
    ResearchOpen Access
    Communications Medicine
    Volume: 4, P: 1-16

  • Innate lymphoid cells are important players in the innate immune response, and might also contribute to inflammatory diseases. This Review discusses what is known about these cells and how they might be targeted in future therapies for these diseases.

    • Medya M. Shikhagaie
    • Kristine Germar
    • Hergen Spits
    Reviews
    Nature Reviews Rheumatology
    Volume: 13, P: 164-173