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Showing 1–3 of 3 results
Advanced filters: Author: Kym Delventhal Clear advanced filters

  • Accorsi et al. show that the apple snail Pomacea canaliculata has eyes similar to humans and can fully regenerate them. They then developed genetic tools to establish these snails as a novel model system to study the mechanisms of eye regeneration

    • Alice Accorsi
    • Brenda Pardo
    • Alejandro Sánchez Alvarado
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-19

  • Genome editing has yet to be performed in non-bilaterian phyla. Here, Ikmi et al. develop techniques to use both TALEN and CRISPR/Cas9 in the sea anemone, Nematostella vectensis, and further leverage a locus expressing an endogenous fluorescent protein as a landing site for homologous recombination-mediated transgenesis.

    • Aissam Ikmi
    • Sean A. McKinney
    • Matthew C. Gibson
    Research
    Nature Communications
    Volume: 5, P: 1-8

  • A comprehensive library encompassing alanine scanning mutations across yeast histones is presented as a Resource that will facilitate screening of chromatin processes. The utility of the library is indicated by screening in cis and in trans for residues that affect histone H3K4 trimethylation, a modification that is associated with actively transcribed genes and known to be mediated by the Set1-COMPASS complex.

    • Shima Nakanishi
    • Brian W Sanderson
    • Ali Shilatifard
    Research
    Nature Structural & Molecular Biology
    Volume: 15, P: 881-888