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Showing 1–3 of 3 results
Advanced filters: Author: Kyoko Matoba Clear advanced filters

  • RaPID (Random non-standard Peptides Integrated Discovery) enables discovery of small macrocyclic peptides binding desired targets. Here, the authors propose lasso-grafting: the RaPID-derived peptides are implanted onto diverse proteins and maintain both the binding properties of the cyclic peptide and the host protein function.

    • Emiko Mihara
    • Satoshi Watanabe
    • Junichi Takagi
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-12

  • Takagi and colleagues report the crystal structure of human Wnt3 in complex with the mouse Frizzled 8 Cys-rich domain, a structural model of the Wnt–Frizzled–LRP6 ternary complex and engineered tagged versions of Wnt3a that retain biological function.

    • Hidenori Hirai
    • Kyoko Matoba
    • Junichi Takagi
    Research
    Nature Structural & Molecular Biology
    Volume: 26, P: 372-379