The surge in metal–organic frameworks for diverse applications has stimulated significant interest in their sustainable and scalable production. Here, the authors develop an ultrasound-assisted two-phase flow reaction platform for the continuous aqueous synthesis of MOFs with sulfonate, imidazolate, and carboxylate ligand chemistries, achieving enhanced nucleation and process efficiency.
- Chao Sun
- Sang T. Pham
- Sean M. Collins
