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Showing 1–3 of 3 results
Advanced filters: Author: L. Ruth Rivkin Clear advanced filters

  • We describe a human DNA methylome atlas based on deep whole-genome bisulfite sequencing, allowing fragment-level analysis of cell-type-specific markers and providing an essential resource for studies of gene regulation and for deconvolution of cell mixtures and liquid biopsies.

    • Netanel Loyfer
    • Judith Magenheim
    • Tommy Kaplan
    ResearchOpen Access
    Nature
    Volume: 613, P: 355-364

  • Eitan et al. discovered genetic variants in the 3′UTR for the gene encoding IL-18 receptor that protect against ALS. The variant 3′UTR destabilizes the mRNA and dampens microglia NF-κB signaling and neurotoxicity, thus emphasizing the value of noncoding genetic association studies.

    • Chen Eitan
    • Aviad Siany
    • Eran Hornstein
    Research
    Nature Neuroscience
    Volume: 25, P: 433-445

  • In this Perspective, the authors develop an integrated framework to understand and predict the joint impacts of climate change and urbanization on biodiversity and ecosystems. They review examples of interacting impacts and present opportunities for future research.

    • Mark C. Urban
    • Marina Alberti
    • Kristien I. Brans
    Reviews
    Nature Climate Change
    Volume: 14, P: 436-447