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Communications Biology (1)

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Improved de novo production of prostaglandin F_2α from glucose with engineered Yarrowia lipolytica strains

Improved de novo production of prostaglandin F2α at titer of 32.63 μg/L in flask cultures is developed via metabolic engineering of Yarrowia lipolytica from glucose, providing a sustainable platform to produce prostaglandins.

Guo-Wei He
La-Mei Ding
Hu-Hu Liu
ResearchOpen Access20 Jan 2026
Communications Biology

Volume: 9, P: 1-11

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Improved de novo production of prostaglandin F2α from glucose with engineered Yarrowia lipolytica strains

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Improved de novo production of prostaglandin F_2α from glucose with engineered Yarrowia lipolytica strains