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Advanced filters: Author: Lane Votapka Clear advanced filters

  • Group-1 influenza A neuramidase proteins have a 150-cavity that can be targeted by drugs, but the 2009 H1N1 virus neuramidase is not thought to have a 150-cavity. Here, biophysical simulations show that the 2009 H1N1 neuramidase exists in solution with an open 150-cavity, which is stabilized by a salt bridge.

    • Rommie E. Amaro
    • Robert V. Swift
    • Robin M. Bush
    ResearchOpen Access
    Nature Communications
    Volume: 2, P: 1-7