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Showing 1–2 of 2 results
Advanced filters: Author: Lara Djakovic Clear advanced filters

  • Herpes simplex virus 1 (HSV-1) infection disrupts transcription termination by RNA Polymerase II. Here, Djakovic et al. identify the immediate-early protein ICP22 protein of HSV-1 to induce open chromatin downstream of genes upon read-through transcription involving the histone chaperone FACT.

    • Lara Djakovic
    • Thomas Hennig
    • Lars Dölken
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-17

  • Here, using computational integration of multi-omics data, the authors provide a detailed transcriptome and translatome of herpes simplex virus 1 (HSV-1), including previously unidentified ORFs and N-terminal extensions. The study also provides a HSV-1 genome browser and should be a valuable resource for further research.

    • Adam W. Whisnant
    • Christopher S. Jürges
    • Lars Dölken
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-14