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Showing 1–2 of 2 results
Advanced filters: Author: Lars Schomacher Clear advanced filters
  • Poly-ADP-ribosylation (PARylation) is a well-known posttranslational modification of proteins. Here the authors show that beyond proteins also mammalian single-stranded DNA is PARylated in vitro and in vivo.

    • Michael U. Musheev
    • Lars Schomacher
    • Christof Niehrs
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-12
  • During oxidative DNA demethylation, Neil DNA glycosylases stimulate processing of abasic sites generated by Tdg, which excises 5-methylcytosine oxidation products generated by Tet dioxygenases, promoting restoration of unmodified cytosines via base excision repair.

    • Lars Schomacher
    • Dandan Han
    • Christof Niehrs
    Research
    Nature Structural & Molecular Biology
    Volume: 23, P: 116-124