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Showing 1–7 of 7 results

Advanced filters: Author: Lasse Sinkkonen Clear advanced filters

Gene-pair expression signatures reveal lineage control

A method to measure reversals in gene expression between cell types is used to identify transcriptional regulators important for lineage specification. The approach should help identify putative factors for direct fate conversion.

Merja Heinäniemi
Matti Nykter
Ilya Shmulevich
Research21 Apr 2013
Nature Methods

Volume: 10, P: 577-583
Park7 deletion leads to sex-specific transcriptome changes involving NRF2-CYP1B1 axis in mouse midbrain astrocytes

Sergio Helgueta
Tony Heurtaux
Lasse Sinkkonen
ResearchOpen Access04 Jan 2025
npj Parkinson's Disease

Volume: 11, P: 1-18
Data-driven inference of Boolean networks from transcriptomes to predict cellular differentiation and reprogramming

Stéphanie Chevalier
Julia Becker
Loïc Paulevé
ResearchOpen Access26 Sept 2025
npj Systems Biology and Applications

Volume: 11, P: 1-16
MicroRNAs control de novo DNA methylation through regulation of transcriptional repressors in mouse embryonic stem cells

Lasse Sinkkonen
Tabea Hugenschmidt
Witold Filipowicz
Research02 Mar 2008
Nature Structural & Molecular Biology

Volume: 15, P: 259-267
Metabolic modelling-based in silico drug target prediction identifies six novel repurposable drugs for melanoma

Tamara Bintener
Maria Pires Pacheco
Thomas Sauter
ResearchOpen Access26 Jul 2023
Cell Death & Disease

Volume: 14, P: 1-13
Focal adhesion kinase plays a dual role in TRAIL resistance and metastatic outgrowth of malignant melanoma

Greta Del Mistro
Shamala Riemann
Dagmar Kulms
ResearchOpen Access12 Jan 2022
Cell Death & Disease

Volume: 13, P: 1-15
Stress-induced inflammation evoked by immunogenic cell death is blunted by the IRE1α kinase inhibitor KIRA6 through HSP60 targeting

Nicole Rufo
Dimitris Korovesis
Patrizia Agostinis
ResearchOpen Access27 Aug 2021
Cell Death & Differentiation

Volume: 29, P: 230-245