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APRIL limits atherosclerosis by binding to heparan sulfate proteoglycans

The heparan sulfate proteoglycan-binding cytokine APRIL has a protective role against atherosclerotic disease.

Dimitrios Tsiantoulas
Mahya Eslami
Christoph J. Binder
Research25 Aug 2021
Nature

Volume: 597, P: 92-96
TREM2 protects from atherosclerosis by limiting necrotic core formation

Piollet, Porsch et al. report that the myeloid receptor TREM2 limits necrotic core formation in atherosclerosis and controls key atherosclerosis-related functions of macrophages, such as efferocytosis, lipid uptake and foam cell survival.

Marie Piollet
Florentina Porsch
Clément Cochain
ResearchOpen Access12 Mar 2024
Nature Cardiovascular Research

Volume: 3, P: 269-282
Mutational landscape of intestinal crypt cells after long-term in vivo exposure to high fat diet

Mathilde Meyenberg
Anna Hakobyan
Joanna I. Loizou
ResearchOpen Access26 Aug 2023
Scientific Reports

Volume: 13, P: 1-12