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Showing 1–11 of 11 results

Advanced filters: Author: Laura Masino Clear advanced filters

The local mechanostructural properties of protein cargoes regulate nucleocytoplasmic transport

The mechanical stability of proteins affects their import into the nucleus. Now it is shown that protein transport in and out of the nucleus depends on the local mechanostability of the protein cargo.

Rafael Tapia-Rojo
Natalie Milmoe
Sergi Garcia-Manyes
ResearchOpen Access30 Apr 2026
Nature Physics

Volume: 22, P: 770-783
Integrase anchors viral RNA to the HIV-1 capsid interior

HIV-1 integrase forms an RNA-binding module on the luminal side of the mature capsid lattice.

Matthew R. Singer
Zhen Li
Peter Cherepanov
ResearchOpen Access18 Feb 2026
Nature

Volume: 652, P: 1068-1075
An intrinsically disordered region mediates RNA-binding selectivity and cellular activities of LARP6

LARP6 is an EMT-associated RNA-binding protein with diverse RNA targets. Here, the authors show that the N-terminal disordered region of LARP6 promotes RNA-binding selectivity by modulating the adjacent La-module and forming auxiliary contacts with RNA.

Federica Capraro
Giancarlo Abis
Faraz K. Mardakheh
ResearchOpen Access19 Feb 2026
Nature Communications

Volume: 17, P: 1-20
ARETA (Alpine caRbon cyclE daTAset): a dataset on physical, chemical and isotopic data of Alpine groundwaters

Marco Donnini
Laura Melelli
Francesco Frondini
ResearchOpen Access24 Mar 2026
Scientific Data

Volume: 13, P: 1-20
Structural basis for Fc receptor recognition of immunoglobulin M

Cryogenic electron microscopy analysis of a complex between the immunoglobulin M (IgM) pentamer and the IgM-specific Fc receptor shows how the receptor specifically recognizes the constant regions of polymeric serum IgM or the membrane-associated B-cell receptor.

Qu Chen
Rajesh P. Menon
Peter B. Rosenthal
Research24 Apr 2023
Nature Structural & Molecular Biology

Volume: 30, P: 1033-1039
TDP-43 loss and ALS-risk SNPs drive mis-splicing and depletion of UNC13A

Risk variants for ALS and FTD in the synaptic gene UNC13A increase the expression of an UNC13A cryptic exon in neurons with TDP-43 depletion.

Anna-Leigh Brown
Oscar G. Wilkins
Pietro Fratta
ResearchOpen Access23 Feb 2022
Nature

Volume: 603, P: 131-137
Mechanism of single-stranded DNA annealing by RAD52–RPA complex

Single-stranded DNA annealing is driven by RAD52 open rings in association with RPA.

Chih-Chao Liang
Luke A. Greenhough
Stephen C. West
ResearchOpen Access24 Apr 2024
Nature

Volume: 629, P: 697-703
Author Correction: TDP-43 loss and ALS-risk SNPs drive mis-splicing and depletion of UNC13A

Anna-Leigh Brown
Oscar G. Wilkins
Pietro Fratta
Amendments and CorrectionsOpen Access18 Jun 2024
Nature

Volume: 631, P: E7
EGCG redirects amyloidogenic polypeptides into unstructured, off-pathway oligomers

Dagmar E Ehrnhoefer
Jan Bieschke
Erich E Wanker
Research30 May 2008
Nature Structural & Molecular Biology

Volume: 15, P: 558-566
Rapid and accurate interpretation of clinical exomes using Phenoxome: a computational phenotype-driven approach

Chao Wu
Batsal Devkota
Mahdi Sarmady
Research09 Jan 2019
European Journal of Human Genetics

Volume: 27, P: 612-620
Determinants of E2-ubiquitin conjugate recognition by RBR E3 ligases

Luigi Martino
Nicholas R. Brown
Katrin Rittinger
ResearchOpen Access08 Jan 2018
Scientific Reports

Volume: 8, P: 1-13