BIN1/M-Amphiphysin2 is a membrane tubulating protein involved in muscle T-tubule biogenesis and whose loss-of-function is associated with centronuclear myopathies. Picas et al.show that BIN1 enhances the recruitment of its binding partner, dynamin, by clustering PtdIns(4,5)P2 in the plasma membrane.
- Laura Picas
- Julien Viaud
- Bruno Goud
