Conventional sensors generate a signal that is directly proportional to the concentration of the target molecule. Now, by means of an enzyme that controls the growth of silver nanocrystals on plasmonic transducers, a nanosensor with sensitivity that is inversely proportional to concentration and that can detect ultralow concentrations of the cancer biomarker prostate-specific antigen in whole serum is demonstrated.
- Laura Rodríguez-Lorenzo
- Roberto de la Rica
- Molly M. Stevens