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Showing 1–2 of 2 results
Advanced filters: Author: Lauren Chessum Clear advanced filters

  • Ikzf2, which encodes the transcription factor Helios, is identified as a crucial regulator of gene expression in maturing cochlear outer hair cells, and overexpression of Ikzf2 in inner hair cells induces prestin expression and electromotility.

    • Lauren Chessum
    • Maggie S. Matern
    • Ronna Hertzano
    Research
    Nature
    Volume: 563, P: 696-700

  • Random mutagenesis can uncover novel genes involved in phenotypic traits. Here the authors perform a large-scale phenotypic screen on over 100 mouse strains generated by ENU mutagenesis to identify mice with age-related diseases, which they attribute to specific mutations revealed by whole-genome sequencing.

    • Paul K. Potter
    • Michael R. Bowl
    • Steve D. M. Brown
    ResearchOpen Access
    Nature Communications
    Volume: 7, P: 1-13