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Showing 1–8 of 8 results

Advanced filters: Author: Laurent Mouchiroud Clear advanced filters

Phylogenetic position of the order Lagomorpha (rabbits, hares and allies)

Dan Graur
Laurent Duret
Manolo Gouy
Research25 Jan 1996
Nature

Volume: 379, P: 333-335
Mitonuclear protein imbalance as a conserved longevity mechanism

Mitochondrial ribosomal proteins have been identified as longevity regulators in C. elegans and mammalian systems, their role in longevity is linked to mitonuclear protein imbalance and the mitochondrial unfolded protein response.

Riekelt H. Houtkooper
Laurent Mouchiroud
Johan Auwerx
Research22 May 2013
Nature

Volume: 497, P: 451-457
Urolithin A induces mitophagy and prolongs lifespan in C. elegans and increases muscle function in rodents

The naturally occurring compound urolithin A has been found to promote mitophagy, thereby increasing lifespan in worms and improving skeletal muscle activity in rodents.

Dongryeol Ryu
Laurent Mouchiroud
Johan Auwerx
Research11 Jul 2016
Nature Medicine

Volume: 22, P: 879-888
Enhancing mitochondrial proteostasis reduces amyloid-β proteotoxicity

Amyloid-β peptide proteopathies disrupt mitochondria, and restoring mitochondrial proteostasis reduces protein aggregation in animal models of amyloid-β disease.

Vincenzo Sorrentino
Mario Romani
Johan Auwerx
Research06 Dec 2017
Nature

Volume: 552, P: 187-193
Microfluidics-enabled phenotyping of a whole population of C. elegans worms over their embryonic and post-embryonic development at single-organism resolution

Maria Cristina Letizia
Matteo Cornaglia
Martin A. M. Gijs
ResearchOpen Access07 May 2018
Microsystems & Nanoengineering

Volume: 4, P: 1-11
An automated microfluidic platform for C. elegans embryo arraying, phenotyping, and long-term live imaging

Matteo Cornaglia
Laurent Mouchiroud
Martin A. M. Gijs
ResearchOpen Access07 May 2015
Scientific Reports

Volume: 5, P: 1-13
A method to identify and validate mitochondrial modulators using mammalian cells and the worm C. elegans

Pénélope A. Andreux
Laurent Mouchiroud
Johan Auwerx
ResearchOpen Access13 Jun 2014
Scientific Reports

Volume: 4, P: 1-10
A screening-based platform for the assessment of cellular respiration in Caenorhabditis elegans

Mitochondrial dysfunction is linked to a range of common disorders, including inherited metabolic diseases, diabetes and cancer. Here, Koopman et al. describe a protocol to study mitochondrial function in C. elegans using the XF96 respirometer.

Mandy Koopman
Helen Michels
Riekelt H Houtkooper
Protocols01 Sept 2016
Nature Protocols

Volume: 11, P: 1798-1816