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Showing 1–3 of 3 results
Advanced filters: Author: Laurin Flemmich Clear advanced filters

  • Small-molecule ligands have been developed that covalently attach to their cognate RNA aptamers in vitro and in living cells. This strategy opens up new avenues for RNA imaging applications (for example, FRAP), for direct fluorescence detection of RNA pull-downs or for covalent RNA-targeted drug design.

    • Raphael Bereiter
    • Laurin Flemmich
    • Ronald Micura
    ResearchOpen Access
    Nature Chemical Biology
    Volume: 21, P: 843-854

  • In humans, protein methyltransferase is responsible for RNA methylation using S-adenosylmethionine as a methyl group donor. Here the authors report a self-methylation activity of a bacterial riboswitch.

    • Laurin Flemmich
    • Sarah Heel
    • Ronald Micura
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-10