Advanced search

Filter By:

Journal Check one or more journals to show results from those journals only.

Choose more journals

Article type Check one or more article types to show results from those article types only.
Subject Check one or more subjects to show results from those subjects only.
Date Choose a date option to show results from those dates only.

Custom date range

Clear all filters
Sort by:
Showing 1–4 of 4 results
Advanced filters: Author: Leah Sibener Clear advanced filters

  • Nature Biotechnology asks a selection of leaders from across biotech to look at the future of the sector and make some predictions for the coming years.

    • Katrine Bosley
    • Charlotte Casebourn
    • Bowen Zhao
    News
    Nature Biotechnology
    Volume: 39, P: 654-660

  • Jonathan Pritchard, Christopher Garcia and colleagues examine associations between different T cell receptor V genes and MHC alleles by eQTL mapping. They find that there are strong associations between MHC variation and T cell receptor gene usage and map these signals to specific MHC amino acids, many of which physically interact with germline-encoded amino acids on the T cell receptor.

    • Eilon Sharon
    • Leah V Sibener
    • Jonathan K Pritchard
    Research
    Nature Genetics
    Volume: 48, P: 995-1002

  • The TCR-peptide-MHC interface is composed of conserved and diverse regions, but the relative contributions of each in shaping T cell recognition remain unclear. Garcia and colleagues show consistent germline interactions between TCR and MHC, but enough flexibility in the TCR-peptide-MHC interface to allow adjustment for different peptides.

    • Jarrett J Adams
    • Samanthi Narayanan
    • K Christopher Garcia
    Research
    Nature Immunology
    Volume: 17, P: 87-94