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Showing 1–3 of 3 results
Advanced filters: Author: Leen Delang Clear advanced filters

  • Here, the authors compare seven low passage Zika virus (ZIKV) strains representing the recently circulating viral genetic diversity of African and Asian strains and find that African ZIKV strains have higher transmissibility in mosquitoes and higher lethality in both adult and fetal mice.

    • Fabien Aubry
    • Sofie Jacobs
    • Louis Lambrechts
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-14

  • SARS-CoV-2 infection can result in severe lung inflammation and pathology, but host response remains incompletely understood. Here the authors show in Syrian hamsters that STAT2 signaling restricts systemic virus dissemination but also drives severe lung injury, playing a dual role in SARS-CoV-2 infection.

    • Robbert Boudewijns
    • Hendrik Jan Thibaut
    • Kai Dallmeier
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-10

  • The findings of a World Health Organization expert working group that is developing animal models to test vaccines and therapeutic agents for the treatment of COVID-19, and their relevance for preclinical testing, are reviewed.

    • César Muñoz-Fontela
    • William E. Dowling
    • Dan H. Barouch
    Reviews
    Nature
    Volume: 586, P: 509-515