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Showing 1–2 of 2 results
Advanced filters: Author: Lena Pfaller Clear advanced filters

  • How much the environment influences inherited adaptive traits is debated and challenging to demonstrate in mammals. Here the authors performed a multigeneration study that failed to morphologically replicate enhanced wound healing response following ancestral liver injury in rats. However, heritable transcriptional effects suggest transmission at the molecular level, albeit of unclear functional relevance.

    • Johanna Beil
    • Juliane Perner
    • Rémi Terranova
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-16

  • Nucleosomes form arrays with even spacing between them in virtually all eukaryotes; however, their biogenesis is incompletely understood. Here the authors show that nucleosome density and DNA sequence along with the Ino80 chromatin remodeling complex play a role in nucleosome array formation in yeast and that the transcriptional machinery disrupts evenly-spaced nucleosomes.

    • Ashish Kumar Singh
    • Tamás Schauer
    • Felix Mueller-Planitz
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-15