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Showing 1–3 of 3 results
Advanced filters: Author: Leonie Flueckiger Clear advanced filters

  • Diffraction-before-destruction of ultrashort X-ray pulses can visualize non-equilibrium processes at the nanoscale with sub-femtosecond precision. Here, the authors demonstrate how the brightness and the spatial resolution of such snapshots can be substantially increased despite ionization.

    • Stephan Kuschel
    • Phay J. Ho
    • Tais Gorkhover
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-8

  • MAL and MyD88 are downstream adaptors of Toll-like receptors (TLR) and the MAL TIR domain forms filaments in vitro, which in turn nucleate the assembly of crystalline arrays of the MyD88 TIR domain. Here, the authors present the structure of these MyD88 TIR crystalline arrays solved by both microcrystal electron diffraction and serial femtosecond crystallography, and they show with mutagenesis experiments that MyD88 interface residues are important for TLR4 signaling in vivo.

    • Max T. B. Clabbers
    • Susannah Holmes
    • Thomas Ve
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-14

  • Emergent nanoscale order in organic materials is typically characterized by small-angle X-ray scattering. Here, angular fluctuations in the diffraction patterns are used to probe the 3D structure of self-assembled lipid membranes, revealing previously inaccessible details on the phase geometry.

    • Andrew V. Martin
    • Alexander Kozlov
    • Connie Darmanin
    ResearchOpen Access
    Communications Materials
    Volume: 1, P: 1-8