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Showing 1–4 of 4 results
Advanced filters: Author: Lies Langouche Clear advanced filters

  • Hyperglycemia often occurs in patients who are acutely ill. This Review details the findings of several recent studies showing that using insulin to maintain normoglycemia for a few days significantly improved survival and morbidity in patients in medical or surgical intensive care units.

    • Lies Langouche
    • Ilse Vanhorebeek
    • Greet Van den Berghe
    Reviews
    Nature Clinical Practice Endocrinology & Metabolism
    Volume: 3, P: 270-278

  • Neuroendocrine responses differ markedly in chronic critical illness compared with acute illness, and the chronic response may be harmful. Hyperglycemia is a major risk factor, and control of blood glucose is important. Because hypothalamic–pituitary axes interact during chronic illness, validating new therapies aimed at correcting multiple endocrine pathways seems warranted.

    • Ilse Vanhorebeek
    • Lies Langouche
    • Greet Van den Berghe
    Reviews
    Nature Clinical Practice Endocrinology & Metabolism
    Volume: 2, P: 20-31

  • In this Review, new insights into the hypothalamic–pituitary–adrenal axis are integrated within a novel conceptual framework that can be used to re-appreciate adrenocortical function and dysfunction in the context of critical illness.

    • Arno Téblick
    • Bram Peeters
    • Greet Van den Berghe
    Reviews
    Nature Reviews Endocrinology
    Volume: 15, P: 417-427