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Generation of modified cows and sheep from spermatid-like haploid embryonic stem cells

Haploid embryonic stem cells for cattle and sheep are produced, opening new reproductive possibilities.

Lei Yang
Anqi Di
Guangpeng Li
Research07 Oct 2025
Nature Biotechnology

P: 1-9
Increased rumen Prevotella enhances BCAA synthesis, leading to synergistically increased skeletal muscle in myostatin-knockout cattle

A study on myostatin knockout cattle reveals increased muscle area and branched-chain amino acids (BCAAs) linked to elevated Prevotella in the rumen microbiota, enhancing BCAA synthesis and transport for improved muscle growth.

Chao Hai
Zhenting Hao
Guangpeng Li
ResearchOpen Access26 Nov 2024
Communications Biology

Volume: 7, P: 1-12

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Generation of modified cows and sheep from spermatid-like haploid embryonic stem cells

Increased rumen Prevotella enhances BCAA synthesis, leading to synergistically increased skeletal muscle in myostatin-knockout cattle

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