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Communications Biology (2)

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B cell heterogeneity in human tuberculosis highlights compartment-specific phenotype and functional roles

Using flow cytometry and transcriptomic analyses, the authors characterize the functional diversity of B cell subsets in the lungs of patients with tuberculosis.

Robert Krause
Paul Ogongo
Al Leslie
ResearchOpen Access16 May 2024
Communications Biology

Volume: 7, P: 1-15
Mycobacterium tuberculosis senses host Interferon-γ via the membrane protein MmpL10

Mycobacterium tuberculosis senses IFN-γ via the membrane protein MmpL10, which results in stimulation of bacterial respiration and virulence gene expression, worsens infection and paradoxically prevents the formation of isoniazid tolerant persisters.

Mohamed Ahmed
Jared Mackenzie
Alasdair Leslie
ResearchOpen Access01 Dec 2022
Communications Biology

Volume: 5, P: 1-10

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B cell heterogeneity in human tuberculosis highlights compartment-specific phenotype and functional roles

Mycobacterium tuberculosis senses host Interferon-γ via the membrane protein MmpL10

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