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Showing 1–6 of 6 results

Advanced filters: Author: Lilach Sheiner Clear advanced filters

Publisher Correction: Numerous rRNA molecules form the apicomplexan mitoribosome via repurposed protein and RNA elements

Shikha Shikha
Victor Tobiasson
Lilach Sheiner
Amendments and CorrectionsOpen Access06 Mar 2025
Nature Communications

Volume: 16, P: 1-2
Engineering Toxoplasma gondii secretion systems for intracellular delivery of multiple large therapeutic proteins to neurons

Toxoplasma gondii secretion systems can be engineered to deliver multiple large therapeutic proteins to neurons in vitro and in vivo.

Shahar Bracha
Hannah J. Johnson
Oded Rechavi
ResearchOpen Access29 Jul 2024
Nature Microbiology

Volume: 9, P: 2051-2072
Numerous rRNA molecules form the apicomplexan mitoribosome via repurposed protein and RNA elements

Structure of the Toxoplasma mitoribosome made of >50 short rRNA molecules reveals evolutionary solutions to rRNA fragmentation: addition of poly A tails to rRNAs, reused rRNA sequences, and repurposing of proteins with transcription factor domains.

Shikha Shikha
Victor Tobiasson
Lilach Sheiner
ResearchOpen Access18 Jan 2025
Nature Communications

Volume: 16, P: 1-13
Structure, assembly and inhibition of the Toxoplasma gondii respiratory chain supercomplex

Here the authors demonstrate that the assembly of mitochondrial respiratory supercomplex (III₂–IV) from Toxoplasma gondii is critical for parasite fitness. They reveal the basis for cytochrome b inhibition by atovaquone and improved ELQ inhibitors.

Andrew E. MacLean
Shikha Shikha
Alexander Mühleip
ResearchOpen Access19 May 2025
Nature Structural & Molecular Biology

Volume: 32, P: 1424-1433
ATP synthase hexamer assemblies shape cristae of Toxoplasma mitochondria

Structural and functional analysis of mitochondria from the human parasite Toxoplasma gondii reveals that its ATP synthase assembles into cyclic hexamers, arranged together in a form of pentagonal pyramids required for maintenance of cristae morphology in Apicomplexa.

Alexander Mühleip
Rasmus Kock Flygaard
Alexey Amunts
ResearchOpen Access05 Jan 2021
Nature Communications

Volume: 12, P: 1-13
Mitochondrial behaviour throughout the lytic cycle of Toxoplasma gondii

Jana Ovciarikova
Leandro Lemgruber
Lilach Sheiner
ResearchOpen Access16 Feb 2017
Scientific Reports

Volume: 7, P: 1-13