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Showing 1–2 of 2 results
Advanced filters: Author: Lilia Boucinha Clear advanced filters

  • The combination of chemotherapy and broad-spectrum antibiotics induces gut microbiota (GM) dysbiosis in acute myeloid leukaemia (AML) leading to additional complications. Here, the authors report the efficacy in GM restoration and safety of autologous faecal microbiota transfer in treated AML patients in a phase II clinical trial.

    • Florent Malard
    • Anne Vekhoff
    • Mohamad Mohty
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-11

  • Here, the authors develop and characterize a mouse microbiota composed of 15 strains representative of the intestinal microbiota found in C57BL/6J specific opportunistic- and pathogen-free (C57Bl/6J SOPF) mice and derive a new standardized gnotobiotic mouse model, called GM15, which recapitulates the phenotypes of SOPF or SPF animals in different animal facilities with improved reproducibility.

    • Marion Darnaud
    • Filipe De Vadder
    • Andrea Tamellini
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-21